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MOTS-c does not produce a dose-dependent linear response where more injections yield proportionally better results

Vitamin B12 helps in the production of brain chemicals and also helps with some crucial brain functions

(7) Ogru E, Wilson J C, Heffernan M, Jiang W J, Chalmers D K, Libinaki R, Ng F (2000) The conformational and biological analysis of a cyclic anti-obesity peptide from the C-terminal domain of human growth hormone The Journal of Peptide Research, 2000 Dec, Volume 56 (Issue 6), Pages 388-97

The action of these enzymes is shown below

Notably, brain IR is implicated in neurodegenerative processes by affecting amyloid-beta metabolism and tau phosphorylation, linking it to both cognitive decline and mood disorders [7, 8]

PMCID: PMC9512238